Unexpected lower level of oral periodontal pathogens in patients with high numbers of systemic diseases.

ABSTRACT:

Background

Periodontal disease is associated with systemic conditions such as diabetes, arthritis, and cardiovascular disease, all diseases with large inflammatory components. Some, but not all, reports show periopathogens Porphyromonas gingivialis and Tannerella forsythia at higher levels orally in people with one of these chronic diseases and in people with more severe cases. These oral pathogens are thought to be positively associated with systemic inflammatory diseases through induction of oral inflammation that works to distort systemic inflammation or by directly inducing inflammation at distal sites in the body. This study aimed to determine if, among patients with severe periodontal disease, those with multi-morbidity (or many chronic diseases) showed higher l

SUBMITTER: Shen MT 

PROVIDER: S-EPMC10351517 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature