Stress specifically deteriorates working memory in peripheral neuropathic pain and fibromyalgia.

ABSTRACT: This study aimed to explore the influence of chronic stress, measured through hair cortisol, on executive functions in individuals with chronic pain. We expected that there would be significant differences in chronic stress and executive functioning between pain patients and healthy controls, as well as between primary and secondary pain classifications. We also hypothesized that hair cortisol concentration was predictive of worse performance on tests of executive functions, controlling for objective and subjective covariates. For this study, 122 participants provided a hair sample (n = 40 with fibromyalgia; n = 24 with peripheral neuropathic pain; n = 58 matched healthy controls). Eighty-four of these participants also completed highly detailed testing of executive fu

SUBMITTER: Jacobsen HB 

PROVIDER: S-EPMC10351603 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature