Exploring risk factors for persistent neurocognitive sequelae after hospitalization for COVID-19.

ABSTRACT:

Objective

In this study of patients hospitalized during acute SARS-CoV2 infection with 6-months of follow-up data, we identified risk factors associated with the development of neuro-PASC.

Methods

We conducted an exploratory, observational single-center cohort study of patients hospitalized for COVID-19 from November 2020 to March 2022. Our primary outcome was persistent neurocognitive symptoms, defined as fatigue, headache, loss of taste/smell, brain fog, confusion, concentration/memory/word finding difficulty, and/or change in speech present at 1-month and persisting for 6-months following acute SARS-CoV2 infection. Secondary outcomes included persistent impairment scores on PROMIS cognitive function and abilities scales. Multivariate logistic regression analyses identifie

SUBMITTER: Ch'en PY 

PROVIDER: S-EPMC10351655 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature