STRategy: A support system for collecting and analyzing next-generation sequencing data of short tandem repeats for forensic science.

ABSTRACT: Short tandem repeats (STRs) are short repeated sequences commonly found in the human genome and valuable in forensic science, used for human identity and relatedness markers. Next-generation sequencing (NGS) technologies, e.g., ForenSeq Signature Prep, can sequence STRs, inferring length-based alleles and single nucleotide polymorphisms (SNPs) and providing valuable insights into population and sub-population structures. Despite the potential benefits of NGS for STRs, no open-source software platform integrates the collection, management, and analysis of STR data from NGS into one place. Users must use multiple programs to process their STR data and then collect the results into a separate database or a file system folder. Moreover, analyzing repeat structures (STR repeat motifs) may requi

SUBMITTER: Kulthammanit N 

PROVIDER: S-EPMC10351723 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature