Reasons for Discontinuation or Change of Selective Serotonin Reuptake Inhibitors in Online Drug Reviews.

ABSTRACT:

Importance

Selective serotonin reuptake inhibitors (SSRIs) are a commonly prescribed medication class to treat a variety of mental disorders. However, adherence to SSRIs is low, and uncovering the reasons for discontinuation among SSRI users is an important first step to improving medication persistence.

Objective

To identify the reasons SSRIs are discontinued or changed, as reported by patients and caregivers in online drug reviews.

Design, setting, and participants

This qualitative study used natural language processing and machine learning to extract mentions of changes in SSRI intake from 667 drug reviews posted on the online health forum WebMD from September 1, 2007, to August 31, 2021. The type of medication change, including discontinuation, switch to another m

SUBMITTER: Golder S 

PROVIDER: S-EPMC10352861 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature