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Association between stress hyperglycemia and outcomes in patients with acute ischemic stroke due to large vessel occlusion.


ABSTRACT:

Aims

This study aimed to evaluate the association between stress hyperglycemia ratio (SHR) and clinical outcomes at 90 days in acute ischemic stroke due to large vessel occlusion receiving endovascular treatment.

Methods

The RESCUE BT trial was a multicenter, randomized, double-blind, placebo-controlled clinical trial, consisting of 948 stroke patients from 55 centers in China. A total of 542 patients with glucose and glycated hemoglobin (HbA1C) values at admission were included in this analysis. SHR, measured by glucose/HbA1C, was evaluated as both a tri-categorical variable (≤1.07 vs. 1.08-1.29 vs. ≥1.30) and a continuous variable. The primary outcome was a favorable functional outcome (modified Rankin Scale [mRS] score ≤2) at 90 days. The secondary outcome included excell

SUBMITTER: Peng Z 

PROVIDER: S-EPMC10352867 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature