Circular RNA as biomarkers for acute ischemic stroke: A systematic review and meta-analysis.

ABSTRACT:

Background

Rapid diagnosis of acute ischemic stroke (AIS) patients is still challenging, and reliable biomarkers are needed. Noncoding RNAs are important for many physiological activities, among which circular RNAs (circRNAs) have been proven to be more tissue-specific and conservative. Many recent studies found the potential of circRNAs as biomarkers for many diseases, including cardiovascular diseases, cancers, and ischemic stroke. This systemic review and meta-analysis aimed to identify circRNAs as potential biomarkers for AIS.

Methods

This study has been prospectively registered in PROSPERO (Registration No. 11 CRD42021288033). Published literature comparing circRNA expression profiles between AIS and non-AIS in human and animal models were retrieved from the articles pu

SUBMITTER: Zhang X 

PROVIDER: S-EPMC10352895 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature