Sandpaper curettage: A simple method to improve PDT outcomes for actinic keratosis.

ABSTRACT:

Introduction

Photodynamic therapy (PDT) is a non-scarring, repeatable, and safe treatment for actinic keratosis (AK), but improvements in efficacy are still needed.

Background

Devices such as steel blades, needle rollers, and lasers are currently used to remove hypertrophic stratum corneum on AKs to improve PDT outcomes. However, curettage with fine sandpaper could be a gentler, effective alternative.

Methods

A retrospective study was designed to compare PDT with or without sandpaper curettage. Patients were selected from a database registry of patients with face and scalp AKs (ClinicalTrials.gov NCT03319251). Patients in Group 1 underwent PDT alone (20% ALA, 15 min; blue light 417 nm, 30 min). Patients in Group 2 were pretreated with gentle sandpaper curettage prior

SUBMITTER: Heusinkveld LE 

PROVIDER: S-EPMC10353292 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature