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Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions.

ABSTRACT: The bacterial pathogen Klebsiella pneumoniae causes nosocomial infections with the acquisition of multidrug resistance, impeding treatment options. This study investigated the effect of zinc limitation on the phosphoproteome of K. pneumoniae using quantitative mass spectrometry. New insight is provided into cellular signaling methods used by the pathogen to respond to nutrient-limited environments.

SUBMITTER: Reitzel C

PROVIDER: S-EPMC10353368 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature

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Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions.

Reitzel Chelsea C Sukumaran Arjun A Zanetti Christina C Muselius Benjamin B Geddes-McAlister Jennifer J

Microbiology resource announcements 20230626 7

The bacterial pathogen Klebsiella pneumoniae causes nosocomial infections with the acquisition of multidrug resistance, impeding treatment options. This study investigated the effect of zinc limitation on the phosphoproteome of K. pneumoniae using quantitative mass spectrometry. New insight is provided into cellular signaling methods used by the pathogen to respond to nutrient-limited environments. ...[more]

PMID: 37358435

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