New medicines for spontaneous preterm birth prevention and preterm labour management: landscape analysis of the medicine development pipeline.

ABSTRACT:

Background

There are few medicines in clinical use for managing preterm labor or preventing spontaneous preterm birth from occurring. We previously developed two target product profiles (TPPs) for medicines to prevent spontaneous preterm birth and manage preterm labor. The objectives of this study were to 1) analyse the research and development pipeline of medicines for preterm birth and 2) compare these medicines to target product profiles for spontaneous preterm birth to identify the most promising candidates.

Methods

Adis Insight, Pharmaprojects, WHO international clinical trials registry platform (ICTRP), PubMed and grant databases were searched to identify candidate medicines (including drugs, dietary supplements and biologics) and populate the Accelerating Innovations

SUBMITTER: McDougall ARA 

PROVIDER: S-EPMC10354994 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature