Ontology highlight
ABSTRACT:
SUBMITTER: Patel K
PROVIDER: S-EPMC10355286 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Patel Khushali K Nguyen Jasmine J Shaha Sumaiyah S Brightwell Amy A Duan Wendy W Zubkowski Ashley A Domingo Ivan K IK Riddell Meghan M
Life science alliance 20230719 10
The syncytiotrophoblast is a human epithelial cell that is bathed in maternal blood on the maternal-facing surface of the human placenta. It therefore acts as a barrier and exchange interface between the mother and fetus. Syncytiotrophoblast dysfunction is a feature of pregnancy pathologies, like preeclampsia. Dysfunctional syncytiotrophoblasts display a loss of microvilli, which is a marker of aberrant apical-basal polarization, but little data exist about the regulation of syncytiotrophoblast ...[more]