Left Ventricular Physiology and Ventricular-Vascular Interactions in Young Patients After Heart Transplantation.

ABSTRACT: Background In patients after heart transplantation, systemic arterial hypertension and enhanced central aortic stiffness contribute to increased ventricular afterload, which might lead to graft dysfunction. The aim of our study was to characterize systemic arterial elastance and its impact on left ventricular function and ventriculo-arterial coupling in a cohort of children, adolescents, and young adults after heart transplantation using invasive conductance catheter technique. Methods and Results Thirty patients who had heart transplants (age, 20.0±6.5 years, 7 female) underwent invasive cardiac catheterization including pressure-volume loop analysis. Load-independent parameters of systolic (ventricular elastance [Ees]) and diastolic (ventricular compliance) function as well as systemic a

SUBMITTER: Latus H 

PROVIDER: S-EPMC10356064 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature