A rise-to-threshold process for a relative-value decision.

ABSTRACT: Whereas progress has been made in the identification of neural signals related to rapid, cued decisions^1-3, less is known about how brains guide and terminate more ethologically relevant decisions in which an animal's own behaviour governs the options experienced over minutes^4-6. Drosophila search for many seconds to minutes for egg-laying sites with high relative value^7,8 and have neurons, called oviDNs, whose activity fulfills necessity and sufficiency criteria for initiating the egg-deposition motor programme⁹. Here we show that oviDNs express a calcium signal that (1) dips when an egg is internally prepared (ovulated), (2) drifts up and down over seconds to minutes-in a manner influenced by the relative value of substrates-as a fly determines

SUBMITTER: Vijayan V 

PROVIDER: S-EPMC10356611 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature