A single-institution retrospective analysis of intraoperative radiation boost during breast-conservation treatment for breast cancer.

ABSTRACT:

Background

As part of a breast-conservation strategy for breast cancer, there are presently no data from randomized controlled studies on the use of intraoperative radiation (IORT) as a tumor bed boost. The effectiveness and safety of IORT as a boost therapy at a tertiary cancer center were retrospectively reviewed in this study.

Methods

Patients had breast-conserving surgery from 2012 to 2016 that included staging of the axillary lymph nodes, a single dose of 20 Gy IORT with 50-kV photons, whole-breast irradiation (WBI), and (neo-)adjuvant systemic treatment (if applicable). During the follow-up patients were monitored for the assessment of acute and late toxicities (using the Common Terminology Criteria for Adverse Events version 4.03). Results included ipsilateral (IBTR),

SUBMITTER: Hochhertz F 

PROVIDER: S-EPMC10356640 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature