Parvalbumin neurons enhance temporal coding and reduce cortical noise in complex auditory scenes.

ABSTRACT: Cortical representations supporting many cognitive abilities emerge from underlying circuits comprised of several different cell types. However, cell type-specific contributions to rate and timing-based cortical coding are not well-understood. Here, we investigated the role of parvalbumin neurons in cortical complex scene analysis. Many complex scenes contain sensory stimuli which are highly dynamic in time and compete with stimuli at other spatial locations. Parvalbumin neurons play a fundamental role in balancing excitation and inhibition in cortex and sculpting cortical temporal dynamics; yet their specific role in encoding complex scenes via timing-based coding, and the robustness of temporal representations to spatial competition, has not been investigated. Here, we address these ques

SUBMITTER: Nocon JC 

PROVIDER: S-EPMC10356822 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature