Correlations between antimicrobial peptides and spectrophotometric skin color parameters in patients with basal cell carcinoma.

ABSTRACT:

Background

Antimicrobial peptides (AMPs) are active molecules in the human innate immune system, that participate in host defense and regulate the inflammation process. Previous reports have confirmed that antimicrobial peptides play a critical role in carcinogenesis.

Objective

The present study aimed to evaluate the correlations between plasma concentrations of AMPs and spectrophotometric parameters of skin color in patients with basal cell carcinoma and compare the results with those of healthy controls.

Methods

The plasma concentrations of cathelicidin and beta-defensin-2 in 100 patients (50 with skin cancer and 50 healthy control subjects) were measured, and skin color parameters were tested using a DermaSpectrophotometer.

Results

In patients with basal cel

SUBMITTER: Fijalkowska M 

PROVIDER: S-EPMC10356866 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature