A Central Auditory Test reveals differences between drug treatment regimens in adults living with HIV.

ABSTRACT:

Objective

This exploratory study examined whether central auditory tests show differences between people living with HIV (PLWH) treated with two predominant antiretroviral drug therapy (ART) regimens.

Design

Cross-sectional.

Study sample

253 PLWH (mean age 39.8 years) from the Shanghai Public Health Clinical Centre, China.

Methods

The Hearing in Noise Test speech reception threshold (SRT) assessed central auditory function and the Montreal Cognitive Assessment (MoCA) assessed cognition. The relationship between ART regimen and SRT was evaluated with multivariable linear regression incorporating age, HIV duration, and peripheral hearing ability. Multivariable logistic regression was used to ascertain if SRT and ART regimen predicted MoCA impairment.

Results</

SUBMITTER: Niemczak CE 

PROVIDER: S-EPMC10356905 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature