Tracking Treatment Response in Cardiac Light-Chain Amyloidosis With Native T1 Mapping.

ABSTRACT:

Importance

Cardiac magnetic resonance (CMR) imaging-derived extracellular volume (ECV) mapping, generated from precontrast and postcontrast T1, accurately determines treatment response in cardiac light-chain amyloidosis. Native T1 mapping, which can be derived without the need for contrast, has demonstrated accuracy in diagnosis and prognostication, but it is unclear whether serial native T1 measurements could also track the cardiac treatment response.

Objective

To assess whether native T1 mapping can measure the cardiac treatment response and the association between changes in native T1 and prognosis.

Design, setting, and participants

This single-center cohort study evaluated patients diagnosed with cardiac light-chain amyloidosis (January 2016 to December 2020) who

SUBMITTER: Ioannou A 

PROVIDER: S-EPMC10357357 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature