The Pediatric Optic Neuritis Prospective Outcomes Study: Two-Year Results.

ABSTRACT:

Purpose

Pediatric optic neuritis (ON) is a rare disease that has not been well characterized. The Pediatric ON Prospective Outcomes Study (PON1) was the first prospective study to our knowledge aiming to evaluate visual acuity (VA) outcomes, including VA, recurrence risk, and final diagnosis 2 years after enrollment.

Design

Nonrandomized observational study at 23 pediatric ophthalmology or neuro-ophthalmology clinics in the United States and Canada.

Participants

A total of 28 (64%) of 44 children initially enrolled in PON1 (age 3-<16 years) who completed their 2-year study visit.

Methods

Participants were treated at the investigator's discretion.

Main outcomes measures

Age-normal monocular high-contrast VA (HCVA). Secondary outcomes included low-contrast

SUBMITTER: Pineles SL 

PROVIDER: S-EPMC10357378 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature