RDN for the treatment of influenza in children: a randomized, double-blinded, parallel-controlled clinical trial.

ABSTRACT:

Background

The morbidity of influenza in children increased rapidly in decade. Reduning injection (RDN), a small but fine Chinese herbal formula, has antipyretic, antiviral, anti-inflammatory effects. We intend to evaluate the efficacy and safety of RDN for the influenza in children versus Oseltamivir, explore the possible antiviral mechanism of RDN and provide evidence-based medical evidence for rational clinical drug usage.

Method

We design a randomized, double-blind, double-dummy, parallel control of positive drug, multi-centre clinical study. According to the formula of mean superiority test, a total of 240 patients with influenza in children will be randomized 1:1 into the experimental group and control group. The experimental group will take RDN and Oseltamivir phospha

SUBMITTER: Yang S 

PROVIDER: S-EPMC10357598 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature