Association of variability in metabolic parameters with the incidence of type 2 diabetes: evidence from a functional community cohort.

ABSTRACT:

Background

To investigate the association of variability in metabolic parameters such as total cholesterol concentrations (TC), uric acid (UA), body mass index (BMI), visceral adiposity index (VAI) and systolic blood pressure (SBP) with incident type 2 diabetes (T2D) and whether variability in these metabolic parameters has additive effects on the risk of T2D.

Methods

Based on the Beijing Functional Community Cohort, 4392 participants who underwent three health examinations (2015, 2016, and 2017) were followed up for incident T2D until the end of 2021. Variability in metabolic parameters from three health examinations were assessed using the coefficient of variation, standard deviation, variability independent of the mean, and average real variability. High variability was d

SUBMITTER: Chen N 

PROVIDER: S-EPMC10357611 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature