Universal screening programme for cytomegalovirus infection in the first trimester of pregnancy: study protocol for an observational multicentre study in the area of Barcelona (CITEMB study).

ABSTRACT:

Introduction

Congenital cytomegalovirus (cCMV) is the leading cause of non-genetic sensorineural hearing loss and one of the main causes of neurological disability. Despite this, no universal screening programme for cCMV has been implemented in Spain. A recent study has shown that early treatment with valaciclovir, initiated in the first trimester and before the onset of signs in the fetus, reduces the risk of fetal infection. This finding favours the implementation of a universal screening programme for cCMV.The aim of this study is to evaluate the performance of a universal screening programme for cCMV during the first trimester of pregnancy in a primary care setting.

Methods and analysis

This is an observational multicentre cohort study. The study will be conducted in fou

SUBMITTER: Sanchez-Duran MA 

PROVIDER: S-EPMC10357649 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature