Adverse events in older adults and the risk of dementia and cognitive decline.

ABSTRACT:

Background

Increasing evidence suggests that stress could be a risk factor for dementia but this might vary by gender. This study investigated whether adverse life events were associated with cognitive decline and dementia in later-life, separately in men and women.

Methods

Participants were 12,789 community-dwelling Australians aged ≥ 70 years. Ten common adverse events in later-life were self-reported. Cognitive decline was defined as a 1.5 SD decline from participants' baseline score in tests of global cognition, psychomotor speed, episodic memory, and executive functioning, which were assessed regularly over a maximum of 10.3 years. Dementia was diagnosed according to DSM-IV criteria.

Results

An increased risk of dementia was observed in participants who experienc

SUBMITTER: Nilaweera D 

PROVIDER: S-EPMC10357969 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature