An Unusual Case Report of a Toddler with Metastatic Neuroblastoma Mimicking Myasthenia Gravis.

ABSTRACT: Pediatric neuroblastoma is famously characterized by an abdominal mass in a toddler with "raccoon eyes," Horner syndrome, and/or opsoclonus myoclonus. However, rare cases may present with non-discrete symptoms and signs which create challenges for timely diagnosis. This case depicts a toddler with bulbar symptoms, including bilateral ptosis, dysphagia, drooling, head tilt and ataxia in a post-viral course mimicking other neurologic diagnoses, including myasthenia gravis. Magnetic resonance imaging (MRI) of the brain and spine uncovered a right adrenal mass along with heterogenous enhancement in multiple vertebral bodies and the clivus, consistent with metastatic disease. A diagnosis of neuroblastoma was confirmed with elevated homovanillic acid (HMA) and vanillylmandelic acid (VMA)

SUBMITTER: Assaf RR 

PROVIDER: S-EPMC10358866 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature