Impact of preventive chemotherapy on Strongyloides stercoralis: A systematic review and meta-analysis.

ABSTRACT:

Background

Strongyloides stercoralis is a neglected soil-transmitted helminth (STH) that leads to significant morbidity in endemic populations. Infection with this helminth has recently been recognised by the World Health Organization (WHO) as a major global health problem to be addressed with ivermectin preventive chemotherapy, and therefore, there is now, the need to develop guidelines for strongyloidiasis control that can be implemented by endemic countries. This study aimed to evaluate the impact of ivermectin preventive chemotherapy (PC) on S. stercoralis prevalence in endemic areas to generate evidence that can inform global health policy.

Methodology/principal findings

This study was a systematic review and meta-analysis. We searched PubMed, EMBASE, Cochrane Central R

SUBMITTER: Stroffolini G 

PROVIDER: S-EPMC10358935 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature