Optimal glycated hemoglobin A1c value for prediabetes and diabetes in patients with pancreatic diseases.

ABSTRACT:

Background

Some articles suggest that using HbA1c alone for diabetes diagnosis is inappropriate. It requires considerable researches to explore the efficacy of HbA1c for diagnosing hyperglycemia in patients with pancreatic disease.

Methods

This study analyzed 732 patients, comprising of 331 without pancreatic disease and 401 patients diagnosed with pancreatic diseases. All participants underwent the HbA1c assay and oral glucose tolerance test. Kappa coefficients were calculated to assess agreement between the HbA1c and glucose criteria. The receiver operating characteristic curve (ROC) was used to calculate the optimal HbA1c value. DeLong test was analyzed to compared the aera under curves (AUCs).

Results

There were 203 (61.3%) patients with NGT, 78 (23.6%) with predi

SUBMITTER: Chen G 

PROVIDER: S-EPMC10358977 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature