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Expression of gasdermin D in clear cell renal cell carcinoma and its effect on its biological function.


ABSTRACT:

SUBMITTER: Zhang J 

PROVIDER: S-EPMC10358983 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Expression of gasdermin D in clear cell renal cell carcinoma and its effect on its biological function.

Zhang Jichi J   Wang Yujie Y   Ma Jun J   Aimudula Ainiwaer A  

Frontiers in oncology 20230706


<h4>Background</h4>Clear cell renal cell carcinoma (ccRCC) is the most common type of renal cell carcinoma, which suffers from the lack of diagnosis and treatment methods, and many patients cannot be diagnosed at first time. Gasdermin D (GSDMD) is involved in inflammatory reactions and pyroptosis and is considered a potential therapeutic target. This paper's aim is to elucidate the expression of GSDMD in clear cell renal cell carcinoma and its value for treatment and prognosis, as well as its im  ...[more]

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