Rianu: Multi-tissue tracking software for increased throughput of engineered cardiac tissue screening.

ABSTRACT:

Background

The field of tissue engineering has provided valuable three-dimensional species-specific models of the human myocardium in the form of human Engineered Cardiac Tissues (hECTs) and similar constructs. However, hECT systems are often bottlenecked by a lack of openly available software that can collect data from multiple tissues at a time, even in multi-tissue bioreactors, which limits throughput in phenotypic and therapeutic screening applications.

Methods

We developed Rianú, an open-source web application capable of simultaneously tracking multiple hECTs on flexible end-posts. This software is operating system agnostic and deployable on a remote server, accessible via a web browser with no local hardware or software requirements. The software incorporates object-tr

SUBMITTER: Murphy JF 

PROVIDER: S-EPMC10359020 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature