Characteristics and influencing factors of ¹¹C-CFT PET imaging in patients with early and late onset Parkinson's disease.

ABSTRACT:

Objective

This study aims to explore the difference between ¹¹C-methyl-N-2β-carbomethoxy-3β-(4-fluorophenyl)-tropanel (¹¹C-CFT) positron emission tomography (PET) imaging in the early-onset Parkinson's disease (EOPD) and late-onset Parkinson's disease (LOPD), and to analyze the correlation between ¹¹C-CFT PET imaging and disease duration, Hoehn & Yahr (H&Y) stage, motor symptoms, and non-motor symptoms in patients with idiopathic Parkinson's disease (PD), so as to explore its application value in assessing the severity of Parkinson's disease.

Materials and methods

A total of 113 patients with idiopathic PD were included in this study. The patients were divided into EOPD and LOPD groups according to the age of 60 years, of which 58 were early-

SUBMITTER: Kangli F 

PROVIDER: S-EPMC10359041 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature