Guideline-Directed Medical Therapy and Long-Term Mortality and Amputation Outcomes in Patients Undergoing Peripheral Vascular Interventions.

ABSTRACT:

Background

Lack of guideline-directed medical therapy (GDMT) in patients undergoing peripheral vascular interventions (PVIs) may increase mortality and amputation risk.

Objectives

The authors sought to study the association between GDMT and mortality/amputation and to examine GDMT variability among providers and health systems.

Methods

We performed an observational study using patients in the Vascular Quality Initiative registry undergoing PVI between 2017 and 2018. Two-year all-cause mortality and major amputation data were derived from Medicare claims data. Compliance with GDMT was defined as receiving a statin, antiplatelet therapy, and angiotensin-converting enzyme inhibitor/angiotensin receptor blocker if hypertensive. Propensity 1:1 matching was applied for GDMT

SUBMITTER: Smolderen KG 

PROVIDER: S-EPMC10359106 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature