A prospective randomized controlled trial evaluating the safety and efficacy of patient blood management program in patients with gynecologic cancer (KGOG 4011/PBM).

ABSTRACT:

Background

Gynecologic cancer has a high frequency of anemia, which is associated with increased morbidity and mortality. Blood transfusion is used to correct anemia, but carries its own side effects and problems in the blood supply have been emerging. As such, methods other than transfusion are needed to correct anemia in patients with cancer.

Primary objective

To determine whether intravenous administration of high-dose iron supplements before and after surgery as a patient blood management program is helpful in correcting anemia and reducing the frequency of transfusion in patients with gynecologic cancer.

Study hypothesis

Patient blood management will reduce the transfusion rate by up to 25%.

Trial design

This prospective, multicenter, interventional, rando

SUBMITTER: Park JY 

PROVIDER: S-EPMC10359505 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature