Association of beta-blockers beyond 1 year after myocardial infarction and cardiovascular outcomes.

ABSTRACT:

Objective

Beta-blockers (BB) are an established treatment following myocardial infarction (MI). However, there is uncertainty as to whether BB beyond the first year of MI have a role in patients without heart failure or left ventricular systolic dysfunction (LVSD).

Methods

A nationwide cohort study was conducted including 43 618 patients with MI between 2005 and 2016 in the Swedish register for coronary heart disease. Follow-up started 1 year after hospitalisation (index date). Patients with heart failure or LVSD up until the index date were excluded. Patients were allocated into two groups according to BB treatment. Primary outcome was a composite of all-cause mortality, MI, unscheduled revascularisation and hospitalisation for heart failure. Outcomes were analysed using Co

SUBMITTER: Ishak D 

PROVIDER: S-EPMC10359586 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature