Transcriptomic regulations of heat stress response in the liver of lactating dairy cows.

ABSTRACT:

Background

The global dairy industry is currently facing the challenge of heat stress (HS). Despite the implementation of various measures to mitigate the negative impact of HS on milk production, the cellular response of dairy cows to HS is still not well understood. Our study aims to analyze transcriptomic dynamics and functional changes in the liver of cows subjected to heat stress (HS). To achieve this, a total of 9 Holstein dairy cows were randomly selected from three environmental conditions - heat stress (HS), pair-fed (PF), and thermoneutral (TN) groups - and liver biopsies were obtained for transcriptome analysis.

Results

Both the dry matter intake (DMI) and milk yield of cows in the HS group exhibited significant reduction compared to the TN group. Through liver tr

SUBMITTER: Li G 

PROVIDER: S-EPMC10360291 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature