Joint association of loneliness and traditional risk factor control and incident cardiovascular disease in diabetes patients.

ABSTRACT:

Aims

To investigate the prospective associations of the loneliness and social isolation scales with cardiovascular disease (CVD) risk in diabetes patients and compare the relative importance of loneliness and social isolation with traditional risk factors. Also, the interactions of loneliness or isolation with the degree of risk factor control in relation to CVD risk were evaluated.

Methods and results

A total of 18 509 participants diagnosed with diabetes from the UK Biobank were included. A two-item scale and a three-item scale were used to assess loneliness and isolation levels, respectively. The degree of risk factor control was defined as numbers of glycated hemoglobin (HbA1c), blood pressure (BP), low-density lipoprotein cholesterol (LDL-C), smoking, and kidney conditi

SUBMITTER: Wang X 

PROVIDER: S-EPMC10361009 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature