Subtractive proteomics analysis to uncover the potent drug targets for distinctive drug design of Candidaauris.

ABSTRACT: Candida auris is a serious health concern of the current world that possesses a serious global health threat and is emerging at a high rate. Available antifungal drugs are failing to combat this pathogen as they are growing resistant to those drugs and some strains have already shown resistance to all three available antifungal drugs in the market. Hence, finding alternative therapies is essential for saving lives from this enemy. To make the development of new treatments easier, we conducted some in silico study of this pathogen to discover possible targets for drug design and also recommended some possible metabolites to test in vivo circumstances. The complete proteome of the representative strain was retrieved, and the duplicate, non-essential, human homologous, no

SUBMITTER: Bappy MNI 

PROVIDER: S-EPMC10361121 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature