A green compliant hand-held selective electrode device for monitoring active pharmaceuticals and the kinetics of their degradation.

ABSTRACT: An in-line smartphone connected to a screen-printed selective electrode hand-held device was used to determine the concentration of distigmine bromide (DB) in its pure and dosage forms as well as its degradation kinetics by continuously measuring the change in the produced emf over time. The main objective, supported by the data presented, is to produce a highly reliable smartphone integrated selective sensor as a portable analyzer with potential high cloud connectivity combining a wide linear dynamic range, the fastest response time with the lowest limits of detection and quantitation while best integrating green analytical chemistry principles. The choice of ionophore used in this approach was guided by computation and the data obtained was compared with traditional analytical techniques

SUBMITTER: Badr ElDin N 

PROVIDER: S-EPMC10361986 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature