Routine vaccination for influenza and pneumococcal disease and its effect on COVID-19 in a population of Dutch older adults.

ABSTRACT:

Objectives

Protective heterologous beneficial effects of vaccines have been reported, and in this study we aimed to assess the impact of routine pneumococcal and influenza vaccination on the incidence and symptom duration of COVID-19 in a population of Dutch older adults.

Methods

This cohort study is a secondary analysis of the BCG-CORONA-ELDERLY study, a randomised controlled trial on the effect of BCG vaccination on the cumulative incidence of respiratory tract infections requiring medical intervention in adults ≥60 years. The primary outcome was the cumulative incidence of a self-reported positive SARS-CoV-2 PCR test, and was assessed using a Fine-Gray competing risks model adjusted for baseline characteristics at enrolment. We analysed data from November 1st 2020 until t

SUBMITTER: Taks EJM 

PROVIDER: S-EPMC10362126 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature