Clinical characteristics and reaction to dopaminergic treatment of drug-naive patients with Parkinson's disease in central China: A cross sectional study.

ABSTRACT:

Background

The symptoms of early Parkinson's disease (PD) are complex and hidden. The aim of this study is to explore and summarize the characteristics of the symptoms of drug naïve patients with PD.

Objectives

and Methods Drug-naïve patients with PD and age-matched healthy controls were recruited from the outpatient clinic of Wuhan Union Hospital. The motor and non-motor symptoms were evaluated for further analysis using Unified Parkinson's Disease Rating Scale (UPDRS) I, II, and III; Sniffin' Sticks Screening 12 test; Mini-Mental State Exam (MMSE); Montreal Cognitive Assessment (MoCA); Hamilton Anxiety Scale (HAMA); and Hamilton Depression Scale (HAMD) scores. The acute levodopa challenge test (ALCT) was adopted to assess the reaction to dopaminergic treatment.

Results<

SUBMITTER: Zeng W 

PROVIDER: S-EPMC10362235 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature