Use of statins and risk of myeloproliferative neoplasms: a Danish nationwide case-control study.

ABSTRACT: Previous studies have indicated a possible cancer-protective effect of statins in solid cancers; however, this has never been investigated in myeloproliferative neoplasms (MPNs). We aimed to investigate the association between statin use and the risk of MPNs in a nested nationwide case-control study, using Danish national population registries. Information on statin use was obtained from the Danish National Prescription Registry, and patients diagnosed with MPNs between 2010 and 2018 were identified from the Danish National Chronic Myeloid Neoplasia Registry. The association between statin use and MPNs was estimated using age- and sex-adjusted odds ratios (ORs) and fully adjusted ORs (aORs), adjusting for prespecified confounders. The study population included 3816 cases with MPNs and 19 0

SUBMITTER: Tuyet Kristensen D 

PROVIDER: S-EPMC10362262 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature