The effects of magnesium sulfate added to epidurally administered local anesthetic on postoperative pain: a systematic review.

ABSTRACT:

Background

This study evaluated the efficacy of epidurally administered magnesium associated with local anesthetics on postoperative pain control.

Methods

The study protocol was registered in PROSPERO as CRD42021231910. Literature searches were conducted on Medline, Cochrane, EMBASE, CENTRAL, and Web of Science for randomized controlled trials comparing epidural administration of magnesium added to local anesthetics for postoperative pain in elective surgical adult patients. Primary outcomes were the time to the first Postoperative (PO) Analgesic Request (TFAR), 24-hour postoperative opioid consumption, and Visual Analog Scale (VAS) scores at the first six and 24 postoperative hours. Secondary outcomes included Postoperative Nausea and Vomiting (PONV), pruritus, and shiverin

SUBMITTER: de Oliveira Filho GR 

PROVIDER: S-EPMC10362454 | biostudies-literature | 2023 Jul-Aug

REPOSITORIES: biostudies-literature