Physical, mechanical, and biological properties of collagen membranes for guided bone regeneration: a comparative in vitro study.

ABSTRACT:

Background

To provide a reference for clinical selection of collagen membranes by analyzing the properties of three kinds of collagen membranes widely used in clinics: Bio-Gide membrane from porcine dermis (PD), Heal-All membrane from bovine dermis (BD), and Lyoplant membrane from bovine pericardium (BP).

Methods

The barrier function of three kinds of collagen membranes were evaluated by testing the surface morphology, mechanical properties, hydrophilicity, and degradation rate of collagen membranes in collagenase and artificial saliva. In addition, the bioactivity of each collagen membrane as well as the proliferation and osteogenesis of MC3T3-E1 cells were evaluated. Mass spectrometry was also used to analyze the degradation products.

Results

The BP membrane had the

SUBMITTER: Shi X 

PROVIDER: S-EPMC10362553 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature