Mapping intron retention events contributing to complex traits using splice quantitative trait locus.

ABSTRACT:

Background

Alternative splicing (AS) of mRNA plays an important roles in transcriptome diversity, involving regulation of plant growth and stress response. Understanding the variation of AS events underlying GWAS loci in a crop population can provide insight into the molecular mechanisms of complex agronomic traits. To date, genome-wide association studies relating AS events to agronomic traits have rarely been conducted at the population level in crops.

Results

Here, a pipeline was constructed to identify candidate AS events related to complex traits. Firstly, ovule transcriptome data were used to characterize intron retention (IR), the predominant type of AS in plants, on a genome-wide scale. This was done in a natural population consisting of 279 upland cotton lines. Seco

SUBMITTER: Wang S 

PROVIDER: S-EPMC10362629 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature