Colorectal adenocarcinoma in Uganda: are right-sided and left-sided colon cancers two distinct disease entities?

ABSTRACT:

Introduction

In Western countries, right-sided colon cancers (RSCC) present at an older age and advanced stage. Researchers believe that there is a difference between left-sided colon cancer (LSCC) and RSCC. In Uganda, however, it is unknown whether differences exist in the pathological profile between RSCC and LSCC. The aim of this study was to determine the differences in clinicopathological characteristics between RSCC and LSCC in Ugandan patients.

Methodology

A cross-sectional study was conducted in which colorectal adenocarcinoma formalin-fixed paraffin-embedded tissue (FFPE) blocks were obtained from 2008 to 2021. Colorectal specimens were obtained from prospectively recruited patients. In the retrospective study arm, FFPE blocks and data were obtained from the archive

SUBMITTER: Wismayer R 

PROVIDER: S-EPMC10362740 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature