Impact of antimicrobial use on abundance of antimicrobial resistance genes in chicken flocks in Vietnam.

ABSTRACT:

Objectives

We investigated longitudinally Vietnamese small-scale chicken flocks in order to characterize changes in antimicrobial resistance gene (ARG) content over their life cycle, and the impact of antimicrobial use (AMU) on an intervention consisting of veterinary advice provision.

Methods

AMU data and faecal samples were collected from 83 flocks (25 farms) at day-old, mid- and late-production (∼4 month cycle). Using high-throughput real-time PCR, samples were investigated for 94 ARGs. ARG copies were related to 16S rRNA and ng of DNA (ngDNA). Impact of AMU and ARGs in day-olds was investigated by mixed-effects models.

Results

Flocks received a mean (standard error, SE) animal daily dose (ADD) of 736.7 (83.0) and 52.1 (9.9) kg in early and late production, respect

SUBMITTER: Nhung NT 

PROVIDER: S-EPMC10362913 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature