Relative Ellipsoid Zone Reflectivity in Macular Telangiectasia Type 2.

ABSTRACT:

Purpose

The relative ellipsoid zone reflectivity (rEZR) has been proposed as an innovative biomarker for photoreceptor integrity. This study evaluates the rEZR in macular telangiectasia type 2 (MacTel) eyes of different disease stages.

Methods

The mean rEZR (ratio ellipsoid zone [EZ]/external limiting membrane [ELM] reflectivity [arbitrary units {AUs}], grey level range = 0-1) was analyzed for an entire spectral domain optical coherence tomography volume scan (global) and for each subfield of the Early Treatment Diabetic Retinopathy Study (ETDRS) grid (topographic) in patients with MacTel and controls. MacTel disease severity was classified according to Gass and Blodi.

Results

Linear mixed-model analysis of 145 eyes of 74 patients and 50 eyes of 25 controls revealed g

SUBMITTER: Goerdt L 

PROVIDER: S-EPMC10362918 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature