Pre-treatment amygdala activation and habituation predict symptom change in post-traumatic stress disorder.

ABSTRACT: Trauma-focused psychotherapy approaches are the first-line treatment option for post-traumatic stress disorder (PTSD); however, up to a third of patients remain symptomatic even after completion of the treatment. Predicting which patients will respond to a given treatment option would support personalized treatments and improve the efficiency of healthcare systems. Although previous neuroimaging studies have examined possible pre-treatment predictors of response to treatment, the findings have been somewhat inconsistent, and no other study has examined habituation to stimuli as a predictor. In this study, 16 treatment-seeking adults (M_Age = 43.63, n = 10 women) with a primary diagnosis of PTSD passively viewed pictures of emotional facial expressions during functional mag

SUBMITTER: Hinojosa CA 

PROVIDER: S-EPMC10363634 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature