Automated detection of cerebral microbleeds on MR images using knowledge distillation framework.

ABSTRACT:

Introduction

Cerebral microbleeds (CMBs) are associated with white matter damage, and various neurodegenerative and cerebrovascular diseases. CMBs occur as small, circular hypointense lesions on T2*-weighted gradient recalled echo (GRE) and susceptibility-weighted imaging (SWI) images, and hyperintense on quantitative susceptibility mapping (QSM) images due to their paramagnetic nature. Accurate automated detection of CMBs would help to determine quantitative imaging biomarkers (e.g., CMB count) on large datasets. In this work, we propose a fully automated, deep learning-based, 3-step algorithm, using structural and anatomical properties of CMBs from any single input image modality (e.g., GRE/SWI/QSM) for their accurate detections.

Methods

In our method, the first step consi

SUBMITTER: Sundaresan V 

PROVIDER: S-EPMC10363739 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature