OpenPBTA: The Open Pediatric Brain Tumor Atlas.
Ontology highlight
ABSTRACT:
SUBMITTER: Shapiro JA
PROVIDER: S-EPMC10363844 | biostudies-literature | 2023 Jul
REPOSITORIES: biostudies-literature
Publications
OpenPBTA: The Open Pediatric Brain Tumor Atlas.
Shapiro Joshua A JA Gaonkar Krutika S KS Spielman Stephanie J SJ Savonen Candace L CL Bethell Chante J CJ Jin Run R Rathi Komal S KS Zhu Yuankun Y Egolf Laura E LE Farrow Bailey K BK Miller Daniel P DP Yang Yang Y Koganti Tejaswi T Noureen Nighat N Koptyra Mateusz P MP Duong Nhat N Santi Mariarita M Kim Jung J Robins Shannon S Storm Phillip B PB Mack Stephen C SC Lilly Jena V JV Xie Hongbo M HM Jain Payal P Raman Pichai P Rood Brian R BR Lulla Rishi R RR Nazarian Javad J Kraya Adam A AA Vaksman Zalman Z Heath Allison P AP Kline Cassie C Scolaro Laura L Viaene Angela N AN Huang Xiaoyan X Way Gregory P GP Foltz Steven M SM Zhang Bo B Poetsch Anna R AR Mueller Sabine S Ennis Brian M BM Prados Michael M Diskin Sharon J SJ Zheng Siyuan S Guo Yiran Y Kannan Shrivats S Waanders Angela J AJ Margol Ashley S AS Kim Meen Chul MC Hanson Derek D Van Kuren Nicholas N Wong Jessica J Kaufman Rebecca S RS Coleman Noel N Blackden Christopher C Cole Kristina A KA Mason Jennifer L JL Madsen Peter J PJ Koschmann Carl J CJ Stewart Douglas R DR Wafula Eric E Brown Miguel A MA Resnick Adam C AC Greene Casey S CS Rokita Jo Lynne JL Taroni Jaclyn N JN
Cell genomics 20230531 7
Pediatric brain and spinal cancers are collectively the leading disease-related cause of death in children; thus, we urgently need curative therapeutic strategies for these tumors. To accelerate such discoveries, the Children's Brain Tumor Network (CBTN) and Pacific Pediatric Neuro-Oncology Consortium (PNOC) created a systematic process for tumor biobanking, model generation, and sequencing with immediate access to harmonized data. We leverage these data to establish OpenPBTA, an open collaborat ...[more]
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