[Depression in patients with epilepsy. Pathophysiological and clinical concepts and therapeutic strategies].

ABSTRACT:

Introduction

Depression and epilepsy are highly prevalent diseases and represent a worldwide public health problem.

Development

A non-systematic search was performed in PubMed (MEDLINE) considering current topics in pathophysiological, clinical concepts and treatment strategies in people with epilepsy and depression.

Results and conclusions

Depression and epilepsy have a bidirectional relationship and share some pathophysiological substrates. Depression is the most common neuropsychiatric manifestation in epilepsy; screening and diagnosis are important to start a timely treatment. Antidepressant drugs does not increase the frequency of seizures, on the contrary, it is believed that antidepressants may help reducing the frequency of seizures. In addition, other antidep

SUBMITTER: Paredes-Aragon E 

PROVIDER: S-EPMC10364072 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature