Case-control investigation of occupational lead exposure and kidney cancer.

ABSTRACT:

Objectives

Lead is a suspected carcinogen that has been inconsistently associated with kidney cancer. To clarify this relationship, we conducted an analysis of occupational lead exposure within a population-based study of kidney cancer using detailed exposure assessment methods.

Methods

Study participants (1217 cases and 1235 controls), enrolled between 2002 and 2007, provided information on their occupational histories and, for selected lead-related occupations, answered questions regarding workplace tasks, and use of protective equipment. Industrial hygienists used this information to develop several estimates of occupational lead exposure, including probability, duration and cumulative exposure. Unconditional logistic regression was used to compute ORs and 95% CIs for dif

SUBMITTER: Callahan CL 

PROVIDER: S-EPMC10364141 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature